The first Cyclospora cayetanensis lineage A genome from an isolate from Mexico

BMC Genomics. 2024 Mar 5;25(1):246. doi: 10.1186/s12864-024-10163-y.

Abstract

Background: Cyclospora cayetanensis is a protozoan parasite that causes intestinal illness in humans worldwide. Despite its global distribution, most genomic data for C. cayetanensis has been obtained from isolates collected in the United States, leaving genetic variability among globally distributed isolates underexplored.

Results: In the present study, the genome of an isolate of C. cayetanensis obtained from a child with diarrhea living in Mexico was sequenced and assembled. Evaluation of the assembly using a lineage typing system recently developed by the Centers for Disease Control and Prevention revealed that this isolate is lineage A.

Conclusions: Given that the only other whole genome assembly available from Mexico was classified as lineage B, the data presented here represent an important step in expanding our knowledge of the diversity of C. cayetanensis isolates from Mexico at the genomic level.

Keywords: Cyclospora cayetanensis; Genome; Lineage A; Mexico.

MeSH terms

  • Child
  • Cyclospora* / genetics
  • Diarrhea
  • Genomics
  • Humans
  • Mexico