Study on red blood cell distribution width in children with severe Mycoplasma pneumoniae pneumonia

Biomark Med. 2024 Jan;18(2):69-77. doi: 10.2217/bmm-2023-0671. Epub 2024 Mar 5.

Abstract

Background: This study aimed to investigate the clinical value of the red blood cell distribution width (RDW) in severe Mycoplasma pneumoniae pneumonia (MPP). Methods: A total of 185 children with diagnosed severe MPP were included. The patients' case records and laboratory examination data were analyzed retrospectively. The children were grouped into quartiles based on RDW. Results: Univariate analysis revealed that RDW was significantly correlated with the Pediatric Risk of Mortality (PRISM) III score, Sepsis-Related Organ Failure Assessment score, incidence of invasive intubation and 30-day in-hospital mortality. After adjustment for the severity of illness, multivariate analysis revealed that the PRISM III score and RDW were factors independently associated with 30-day in-hospital mortality. Conclusion: This study revealed that RDW could be correlated with the long-term prognosis and severity of severe MPP.

Keywords: China; Mycoplasma pneumoniae pneumonia; children; red cell distribution width; retrospective; severity.

MeSH terms

  • Child
  • Erythrocyte Indices
  • Erythrocytes
  • Humans
  • Mycoplasma pneumoniae*
  • Pneumonia* / diagnosis
  • Prognosis
  • Retrospective Studies
  • Risk Factors