Spinal Cord Injury: Emerging Technologies

Andrew M Hersh; Carly Weber-Levine; Kelly Jiang; Nicholas Theodore

doi:10.1016/j.nec.2023.10.001

Spinal Cord Injury: Emerging Technologies

Neurosurg Clin N Am. 2024 Apr;35(2):243-251. doi: 10.1016/j.nec.2023.10.001. Epub 2023 Nov 10.

Authors

Andrew M Hersh¹, Carly Weber-Levine², Kelly Jiang³, Nicholas Theodore⁴

Affiliations

¹ Department of Neurosurgery, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 7-113, Baltimore, MD 21287, USA. Electronic address: https://twitter.com/AndrewMHersh.
² Department of Neurosurgery, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 7-113, Baltimore, MD 21287, USA.
³ Department of Neurosurgery, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 7-113, Baltimore, MD 21287, USA. Electronic address: https://twitter.com/kellyjjiang.
⁴ Department of Neurosurgery, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 7-113, Baltimore, MD 21287, USA; Orthopaedic Surgery & Biomedical Engineering, Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: theodore@jhmi.edu.

PMID: 38423740
DOI: 10.1016/j.nec.2023.10.001

Abstract

The mainstay of treatment for spinal cord injury includes decompressive laminectomy and elevation of mean arterial pressure. However, outcomes often remain poor. Extensive research and ongoing clinical trials seek to design new treatment options for spinal cord injury, including stem cell therapy, scaffolds, brain-spine interfaces, exoskeletons, epidural electrical stimulation, ultrasound, and cerebrospinal fluid drainage. Some of these treatments are targeted at the initial acute window of injury, during which secondary damage occurs; others are designed to help patients living with chronic injuries.

Keywords: CSF; Injury; SCI; Spine; Stem cell; Trauma; Ultrasound.

Publication types

Review

MeSH terms

Decompression, Surgical
Humans
Spinal Cord / surgery
Spinal Cord Injuries* / therapy
Spine