The estrogen receptor and metabolism

Womens Health (Lond). 2024 Jan-Dec:20:17455057241227362. doi: 10.1177/17455057241227362.

Abstract

Across the globe, metabolic syndrome, hyperuric acid, and their related diseases, such as cardiovascular disease, diabetes, and insulin resistance, are increasing in incidence due to metabolic imbalances. Due to the pathogenesis, women are more prone to these diseases than men. As estrogen levels decrease after menopause, obesity and metabolic disorders are more likely to occur. Men are also affected by hyperuric acid. To provide ideas for the prevention and treatment of metabolic syndrome and hyperuricemia, this article reviews and analyzes the relationship between estrogen receptors, metabolic syndrome, and hyperuricemia.

Keywords: estrogen; estrogen receptors; hypertension; hyperuricemia; metabolic syndrome.

Plain language summary

Influence of estrogen receptor on metabolic syndrome and hyperuricemiaA narrative review discusses the mechanism of estrogen and estrogen receptors for metabolic syndrome and hyperuric acid, and highlights the important for prevention and treatment of metabolic balances.

Publication types

  • Review

MeSH terms

  • Female
  • Humans
  • Hyperuricemia* / epidemiology
  • Insulin Resistance*
  • Male
  • Metabolic Syndrome* / epidemiology
  • Metabolic Syndrome* / metabolism
  • Obesity
  • Receptors, Estrogen / metabolism

Substances

  • Receptors, Estrogen