Research progress of procyanidins in repairing cartilage injury after anterior cruciate ligament tear

Hanlin Chen; Jingrui Li; Shaofei Li; Xiaoqi Wang; Ge Xu; Molan Li; Guangjie Li

doi:10.1016/j.heliyon.2024.e26070

Research progress of procyanidins in repairing cartilage injury after anterior cruciate ligament tear

Heliyon. 2024 Feb 18;10(4):e26070. doi: 10.1016/j.heliyon.2024.e26070. eCollection 2024 Feb 29.

Authors

Hanlin Chen^{1

2}, Jingrui Li^{1

2}, Shaofei Li^{1

2}, Xiaoqi Wang³, Ge Xu^{1

2}, Molan Li^{1

2}, Guangjie Li¹

Affiliations

¹ The First Hospital of Lanzhou University, Lanzhou, China.
² Major in Clinical Medicine, First Clinical Medical College of Lanzhou University, Lanzhou, China.
³ Major in Clinical Medicine, Second Clinical Medical College of Lanzhou University, Lanzhou, China.

Abstract

Anterior cruciate ligament (ACL) tear is a common sports-related injury, and cartilage injury always emerges as a serious complication following ACL tear, significantly impacting the physical and psychological well-being of affected individuals. Over the years, efforts have been directed toward finding strategies to repair cartilage injury after ACL tear. In recent times, procyanidins, known for their anti-inflammatory and antioxidant properties, have emerged as potential key players in addressing this concern. This article focuses on summarizing the research progress of procyanidins in repairing cartilage injury after ACL tear. It covers the roles, mechanisms, and clinical significance of procyanidins in repairing cartilage injury following ACL tear and explores the future prospects of procyanidins in this domain. This review provides novel insights and hope for the repair of cartilage injury following ACL tear.

Keywords: Anterior cruciate ligament tear; Hydrogels; Inflammation; Repair of cartilage injury; procyanidins.

Publication types

Review