Characteristics of tin-containing fluoride toothpastes related to erosive tooth wear protection

Letícia Oba Sakae; Cláudia Allegrini Kairalla; Ítallo Emídio Lira Viana; Thiago Saads Carvalho; Samira Helena Niemeyer; Anderson Takeo Hara; Taís Scaramucci

doi:10.1016/j.jdent.2024.104901

Characteristics of tin-containing fluoride toothpastes related to erosive tooth wear protection

J Dent. 2024 Apr:143:104901. doi: 10.1016/j.jdent.2024.104901. Epub 2024 Feb 27.

Authors

Letícia Oba Sakae¹, Cláudia Allegrini Kairalla¹, Ítallo Emídio Lira Viana², Thiago Saads Carvalho³, Samira Helena Niemeyer³, Anderson Takeo Hara⁴, Taís Scaramucci⁵

Affiliations

¹ Department of Restorative Dentistry, University of São Paulo, School of Dentistry, Av. Prof. Lineu Prestes 2227, São Paulo, SP 05508-000, Brazil.
² Department of Restorative Dentistry, University of São Paulo, School of Dentistry, Av. Prof. Lineu Prestes 2227, São Paulo, SP 05508-000, Brazil; Department of Comprehensive Care, Division of Operative Dentistry, Tufts University School of Dental Medicine, 1 Kneeland Street, Boston, MA 02111, USA.
³ Department of Restorative, Preventive and Pediatric Dentistry, University of Bern, Freiburgstrasse 7, CH-3010 Bern, Switzerland.
⁴ Department of Cariology, Operative Dentistry and Dental Public Health, Oral Health Research Institute, Indiana University School of Dentistry, 415 Lansing Street, Indianapolis, IN 46202, USA.
⁵ Department of Restorative Dentistry, University of São Paulo, School of Dentistry, Av. Prof. Lineu Prestes 2227, São Paulo, SP 05508-000, Brazil. Electronic address: tais.sca@usp.br.

PMID: 38417610
DOI: 10.1016/j.jdent.2024.104901

Abstract

Objectives: To assess the effect of different tin-containing toothpastes on the control of erosive tooth wear in enamel and dentin.

Methods: Enamel and dentin slabs were randomly distributed into 7 experimental groups (n = 10/substrate): C-: negative control (Artificial saliva); AmF (regular fluoridated toothpaste without tin); Sn-1 (SnF₂/NaF); Sn-2 (SnF₂/NaF/SnCl₂); Sn-3 (SnCl₂/NaF); Sn-4 (SnF₂/SnCl₂); Sn-5 (SnCl₂/AmF/NaF/chitosan). Specimens were submitted to 5-day erosion-abrasion cycling. Surface loss (SL) was determined with an optical profilometer. Tin deposition on the tooth surfaces and some characteristics of the toothpastes (pH, potentially available F^-, %weight of solid particles, and RDA) were also assessed. Data were statistically analyzed (α = 0.05).

Results: For enamel, the Sn-2 presented the lowest SL, not differing significantly from AmF, C+, and Sn-3. The SL of these groups was significantly lower than the C-, except for Sn-3. Sn-1 and Sn-4 were also not significantly different from C-. For dentin, C- significantly showed the highest SL values, whilst, Sn-1 presented the lowest SL, not differing significantly from AmF, Sn-2, C+, and Sn-3. There was a significant positive association between enamel SL and the pH and tin deposition. Dentin SL was significantly negatively associated with the %weight of solid particles and RDA.

Conclusions: Most of the tin-toothpastes were able to exhibit some protection against ETW. In this process, the toothpastes characteristics play a role, as lower enamel SL was significantly associated with lower pH values and tin deposition; and lower dentin SL was associated with higher %weight of solid particles and RDA of the toothpastes.

Clinical significance: Tin-containing toothpastes can be used for erosive tooth wear protection, but our study showed that their effect depends on the pH, amount of tin deposition, % weight of solid particles and RDA of the toohpastes.

Keywords: Dental erosion; Erosive tooth wear; Fluoride; Tin; Tooth abrasion; Toothpaste.

MeSH terms

Fluorides / pharmacology
Humans
Sodium Fluoride / pharmacology
Tin
Tin Compounds*
Tin Fluorides / pharmacology
Tooth Abrasion* / prevention & control
Tooth Erosion* / prevention & control
Tooth Wear*
Toothbrushing
Toothpastes / pharmacology

Substances

Tin Fluorides
stannous chloride
Toothpastes
Fluorides
Tin
Sodium Fluoride
Tin Compounds