Abstract
Arboviruses pose a significant threat to public health globally, demanding innovative approaches for their control. For this, a better understanding of the complex web of interactions established in arbovirus-infected mosquitoes is fundamental. High-throughput analyses allow a genome-wide view of arbovirus-induced alterations at different gene expression levels. This review provides a comprehensive perspective into the current literature in transcriptome and proteome landscapes in mosquitoes infected with arboviruses. It also proposes a coordinated research effort to define the critical nodes that determine arbovirus infection and transmission.
Keywords:
arbovirus; mosquitoes; proteome; transcriptome; vector; vector-borne diseases.
Copyright © 2024 Puig-Torrents and Díez.
Grants and funding
The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work has received funding by “la Caixa” Foundation (LCF/PR/HR23/52430003), the Spanish Ministry of Science and Innovation (PID2022-136939OB-I00/MICIN/AEI/10.13039/501100011033 and “ERDF a way of making Europe”, and PID2019-106959RBI00/MICIN/AEI/10.13039/ 501100011033), by the 2021 SGR 00176 grant from the Departament de Recerca i Universitats de la Generalitat de Catalunya and by an institutional “Unidad de Excelencia María de Maeztu,” funded by the MCIN and the AEI ( doi: 10.13039/501100011033, ref: CEX2018-000792-M). MP-T was a recipient of an FPI fellowship from the Spanish Ministry of Science and Innovation (PRE2020-093049).