Proteomic dataset for decellularization of porcine auricular cartilage

BMC Res Notes. 2024 Feb 27;17(1):58. doi: 10.1186/s13104-024-06716-9.

Abstract

Objectives: Osteoarthritis (OA) is a major concern in the United States and worldwide. Development and validation of robust decellularization techniques is critical in generating suitable bioscaffolds for future OA treatment options.

Data descriptions: In the present study, proteins from porcine auricular cartilage before and after decellularization were extracted, digested, and identified using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The data represents protein profiles of both non-decellularized and decellularized porcine auricular cartilage. This data is intended to be useful to scientists who are interesting in generating biomaterials for potential relevant clinical applications using decellularized cartilage tissue.

Keywords: Cartilage; Decellularization; LC-MS/MS; Osteoarthritis; Porcine; Proteomics.

MeSH terms

  • Animals
  • Chromatography, Liquid
  • Ear Cartilage*
  • Osteoarthritis*
  • Proteomics
  • Swine
  • Tandem Mass Spectrometry
  • Tissue Engineering / methods