[Research progress on the effect of common metabolism-related comorbidities on health outcomes and management strategies in patients with chronic hepatitis B]

Zhonghua Liu Xing Bing Xue Za Zhi. 2024 Feb 10;45(2):319-324. doi: 10.3760/cma.j.cn112338-20230518-00309.
[Article in Chinese]

Abstract

With the increasing life expectancy and lifestyle changes of patients with chronic hepatitis B (CHB), the significance of comorbidities of chronic non-communicable diseases (NCDs) in disease progression and health prognosis of CHB patients is gaining prominence. This study aims to explore the association between CHB and NCDs comorbidities, focusing on the impact of common metabolism-related diseases, such as metabolic syndrome and diabetes, on the health outcomes of CHB patients. We also summarize studies on integrating the management of comorbidities in CHB patients and provide relevant recommendations for effective management. The findings of this study serve as a foundation for understanding the clinical characteristics and prevalence trends, reducing the disease burden of comorbidities among CHB patients, and establishing a comprehensive and coordinated management system for comorbidities.

随着慢性乙型肝炎(CHB)患者期望寿命的延长和生活方式的改变,慢性非传染性疾病(NCDs)共病在CHB患者疾病进展和健康预后的重要性逐渐增加。本文对CHB和NCDs共病相关研究进行综述,探讨了共患如MS、糖尿病等常见代谢相关疾病对CHB患者健康结局的影响,总结了目前CHB共病管理的研究现状并提出了相关建议,为未来明确CHB患者共病的临床特征和流行趋势,降低CHB共病患者疾病负担,建立系统性共病联合管理体系提供依据。.

Publication types

  • English Abstract

MeSH terms

  • Comorbidity
  • Diabetes Mellitus* / epidemiology
  • Hepatitis B virus
  • Hepatitis B, Chronic* / epidemiology
  • Hepatitis B, Chronic* / therapy
  • Humans
  • Outcome Assessment, Health Care
  • Prognosis