Pulmonary Artery Hypertension: Fifty Years Following Pneumonectomy in Infancy

Matthew Seplowe; Ameesh Isath; Liana Michaud; William H Frishman; Avi Levine; Wilbert S Aronow; Gregg M Lanier

doi:10.1097/CRD.0000000000000678

Pulmonary Artery Hypertension: Fifty Years Following Pneumonectomy in Infancy

Cardiol Rev. 2024 Feb 27. doi: 10.1097/CRD.0000000000000678. Online ahead of print.

Authors

Matthew Seplowe¹, Ameesh Isath², Liana Michaud¹, William H Frishman¹, Avi Levine², Wilbert S Aronow^{1

2}, Gregg M Lanier^{1

2}

Affiliations

¹ From the Department of Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY.
² Departments of Cardiology and Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY.

PMID: 38411185
DOI: 10.1097/CRD.0000000000000678

Abstract

Pulmonary hypertension (PH) may be the result of many different pathological processes. PH is a rare but recognized vascular complication following major lung resection. We describe the diagnosis and management of moderate PH resulting more than 50 years in a patient who underwent a total unilateral pneumonectomy in infancy. Unfortunately, patients who undergo pneumonectomy will likely go on to develop PH and their functional status will be greatly impacted. In the case presented, we report on a patient whose PH and symptoms improved following off-label WHO group 1 treatment.