Whole-body MRI in oncology: A comprehensive review

Clin Imaging. 2024 Apr:108:110099. doi: 10.1016/j.clinimag.2024.110099. Epub 2024 Feb 7.

Abstract

Whole-Body Magnetic Resonance Imaging (WB-MRI) has cemented its position as a pivotal tool in oncological diagnostics. It offers unparalleled soft tissue contrast resolution and the advantage of sidestepping ionizing radiation. This review explores the diverse applications of WB-MRI in oncology. We discuss its transformative role in detecting and diagnosing a spectrum of cancers, emphasizing conditions like multiple myeloma and cancers with a proclivity for bone metastases. WB-MRI's capability to encompass the entire body in a singular scan has ushered in novel paradigms in cancer screening, especially for individuals harboring hereditary cancer syndromes or at heightened risk for metastatic disease. Additionally, its contribution to the clinical landscape, aiding in the holistic management of multifocal and systemic malignancies, is explored. The article accentuates the technical strides achieved in WB-MRI, its myriad clinical utilities, and the challenges in integration into standard oncological care. In essence, this review underscores the transformative potential of WB-MRI, emphasizing its promise as a cornerstone modality in shaping the future trajectory of cancer diagnostics and treatment.

Keywords: Bone metastases; Cancer screening; Multiple myeloma; Oncology; Whole-body MRI.

Publication types

  • Review

MeSH terms

  • Bone Neoplasms* / pathology
  • Humans
  • Magnetic Resonance Imaging / methods
  • Multiple Myeloma*
  • Radionuclide Imaging
  • Whole Body Imaging / methods