Outcome of malignant lymphoma in Ukraine. Analysis of 563 cases registered in the Ukrainian Lymphoma Registry in 2019-2021

Yana Stepanishyna; Martina Manni; Monica Civallero; Nazar Shokun; Tetiana Skrypets; Alevtyna Burtna; Natalia Shapovalenko; Iryna Tytorenko; Olena Aleksyk; Yan Pastushenko; Hanna Gubareva; Kateryna Moiseienko; Tetyana Kadnikova; Timur Rudyuk; Kateryna Filonenko; Arina Martynchyk; Olga Novosad; Giulia R Galli; Irina Kryachok; Massimo Federico

doi:10.1111/bjh.19352

Outcome of malignant lymphoma in Ukraine. Analysis of 563 cases registered in the Ukrainian Lymphoma Registry in 2019-2021

Br J Haematol. 2024 Feb 23. doi: 10.1111/bjh.19352. Online ahead of print.

Authors

Yana Stepanishyna^{1

2}, Martina Manni³, Monica Civallero⁴, Nazar Shokun¹, Tetiana Skrypets⁵, Alevtyna Burtna¹, Natalia Shapovalenko⁶, Iryna Tytorenko⁶, Olena Aleksyk⁶, Yan Pastushenko⁶, Hanna Gubareva⁷, Kateryna Moiseienko¹, Tetyana Kadnikova⁶, Timur Rudyuk⁶, Kateryna Filonenko⁸, Arina Martynchyk⁹, Olga Novosad¹⁰, Giulia R Galli¹¹, Irina Kryachok⁶, Massimo Federico⁴

Affiliations

¹ Department of Bone Marrow Transplant, National Cancer Institute, Kyiv, Ukraine.
² Department of Hematology, Jules Bordet Institute, Brussels, Belgium.
³ Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy.
⁴ Surgical, Medical and Dental Department of Morphological Sciences related to Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.
⁵ Hematology Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', Bari, Italy.
⁶ Department of Oncohematology, National Cancer Institute, Kyiv, Ukraine.
⁷ Department of medical statistics and national cancer register, National Cancer Institute, Kyiv, Ukraine.
⁸ Department of Hematology and Transplantology, University Clinical Center, Gdansk, Poland.
⁹ Department of Hematology, Austin Health, Melbourne, Australia.
¹⁰ Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.
¹¹ Department of Biological and Environmental Sciences and Technologies, University of Salento, Lecce, Italy.

PMID: 38400556
DOI: 10.1111/bjh.19352

Abstract

We report the outcome of 563 cases of newly diagnosed lymphoma registered in 2019-2021, including 176 cases (31.2%) of Hodgkin lymphoma (HL), 130 (23.1%) of diffuse large B-cell lymphoma (DLBCL), 28 (5%) of follicular lymphoma (FL), 16 (2.9%) of mantle cell lymphoma (MCL) and 20 (3.5%) of peripheral T-cell lymphoma (PTCL). After a median follow-up of 30.1 months (95% CI: 28.8-31.3), the 3-year overall survival rates were 95%, 83%, 86%, 100%, 61% and 42% for HL, DLBCL, CLL, FL, MCL and PTCL respectively. These data offer valuable information on the curability of lymphoma patients in Ukraine, in a real-world setting.

Keywords: lymphoma registry; malignant lymphoma; survival outcomes.

Grants and funding

Associazione Angela Serra for Cancer research, Modena, Italy