CT-optimal touch and chronic pain experience in Parkinson's Disease; An intervention study

PLoS One. 2024 Feb 23;19(2):e0298345. doi: 10.1371/journal.pone.0298345. eCollection 2024.

Abstract

One of the most underdiagnosed and undertreated non-motor symptoms of Parkinson's Disease is chronic pain. This is generally treated with analgesics which is not always effective and can cause several side-effects. Therefore, new ways to reduce chronic pain are needed. Several experimental studies show that CT-optimal touch can reduce acute pain. However, little is known about the effect of CT-optimal touch on chronic pain. The aim of the current study is to investigate whether CT-optimal touch can reduce the chronic pain experience in Parkinson patients. In this intervention study, 17 Parkinson patients underwent three conditions; no touch, CT-optimal touch and CT non-optimal touch with a duration of one week each. During each touch week, participants received touch from their partners twice a day for 15 minutes. Results show that both types of touch ameliorate the chronic pain experience. Furthermore, it appears that it is slightly more beneficial to apply CT-optimal touch also because it is perceived as more pleasant. Therefore, we argue that CT-optimal touch might be used when immediate pain relief is needed. Importantly, this study shows that CT-optimal touch can reduce chronic pain in Parkinson's Disease and can be administered by a partner which makes it feasible to implement CT-optimal touch as daily routine.

MeSH terms

  • Analgesics
  • Chronic Pain* / therapy
  • Emotions
  • Humans
  • Parkinson Disease* / complications
  • Tomography, X-Ray Computed
  • Touch Perception*

Substances

  • Analgesics

Grants and funding

Funding was obtained by Meijer, Dijkerman and Smagt. There is no Grant number. The Dutch Stichting Parkinsonfonds offered the Grant. https://www.parkinsonfonds.nl/. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.