CSMed® wound dressing for prophylaxis and management of radiation dermatitis in breast and head-neck cancer patients: a single hospital prospective clinical trial

J Cancer Res Clin Oncol. 2024 Feb 23;150(2):101. doi: 10.1007/s00432-024-05624-6.

Abstract

Purpose: CSMed® wound dressing, a dressing with various herb extracts, was tested for its therapeutic effect in radiation dermatitis of breast and head-and-neck cancer patients.

Methods: This study included 20 breast cancer patients and 10 head-and-neck cancer patients. Half of the irradiated area was covered with CSMed® and the other half was under routine treatment. The severity of radiation dermatitis was evaluated with radiation therapy oncology group (RTOG) grade throughout the treatment and the follow-up period. The RTOG grade between the dressed and undressed area were compared to illustrate the therapeutic effect of CSMed® dressing.

Results: The results showed that CSMed® dressed area had significant lower RTOG score at 3-7 weeks and final record during the treatment, and 1-3 weeks during follow-up than undressed area.

Conclusions: This indicated that CSMed® can delay the onset, reduce the severity, and enhance healing of radiation dermatitis. CSMed® can be used for prophylaxis and management of radiation dermatitis.

Keywords: Breast cancer; CSMed®; Head-and-neck cancer; Radiation dermatitis; Radiotherapy.

Publication types

  • Clinical Trial

MeSH terms

  • Bandages
  • Breast Neoplasms* / radiotherapy
  • Female
  • Head and Neck Neoplasms* / radiotherapy
  • Hospitals
  • Humans
  • Prospective Studies
  • Radiodermatitis* / etiology
  • Radiodermatitis* / prevention & control