Editorial: Progress and challenges in computational structure-based design and development of biologic drugs

Traian Sulea; Sandeep Kumar; Daisuke Kuroda

doi:10.3389/fmolb.2024.1360267

Editorial: Progress and challenges in computational structure-based design and development of biologic drugs

Front Mol Biosci. 2024 Feb 7:11:1360267. doi: 10.3389/fmolb.2024.1360267. eCollection 2024.

Authors

Traian Sulea¹, Sandeep Kumar², Daisuke Kuroda³

Affiliations

¹ Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, QC, Canada.
² Computational Protein Design and Modeling, Computational Science, Moderna Therapeutics, Cambridge, MA, United States.
³ Research Center of Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, Japan.

No abstract available

Keywords: binding affinity; developability; in silico method; machine learning; molecular modeling; molecular simulations; specificity; therapeutic antibody.

Publication types

Editorial

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. DK acknowledges support from Japan Agency for Medical Research and Development (JP23wm0325047).