Association between bacterial vaginosis with human papillomavirus in the United States (NHANES 2003-2004)

Jie Qi; Congwei Dai; Liyun Song; Junqin Zhang

doi:10.1186/s12905-024-02956-w

Association between bacterial vaginosis with human papillomavirus in the United States (NHANES 2003-2004)

BMC Womens Health. 2024 Feb 22;24(1):138. doi: 10.1186/s12905-024-02956-w.

Authors

Jie Qi¹, Congwei Dai², Liyun Song¹, Junqin Zhang¹

Affiliations

¹ Department of Gynecology, Hebei General Hospital, Shijiazhuang, 050000, China.
² Department of Gynecology, Hebei General Hospital, Shijiazhuang, 050000, China. dcw8031@126.com.

Abstract

Background: The balance of vaginal microecology is closely related to human papillomavirus (HPV) infection and cervical lesions. This study aims to investigate the relationship between bacterial vaginosis (BV) and HPV infection.

Methods: In total, 1,310 individuals from the National Health and Nutrition Examination Survey (NHANES, 2003-2004) were included in this study. Logistic regression and subgroup analyses were used to examine the association between BV and HPV infection.

Results: A significant positive association was observed between BV and HPV infection in women after adjustment for other confounders (OR = 1.47, 95% confidence interval [CI]: 1.15-1.88). In subgroup analyses, we have found this positive correlation was most prominent among Mexican Americans (OR = 1.83, 95% CI: 1.08-3.08) and non-Hispanic blacks (OR = 1.81, 95% CI: 1.08-3.04).

Conclusions: This cross-sectional study demonstrated a positive association between BV and HPV infection in women.

Keywords: Bacterial vaginosis; HPV; Logistic model; NHANES (National Health and Nutrition Examination Survey).

MeSH terms

Cross-Sectional Studies
Female
Human Papillomavirus Viruses
Humans
Nutrition Surveys
Papillomavirus Infections* / complications
Papillomavirus Infections* / diagnosis
Papillomavirus Infections* / epidemiology
United States / epidemiology
Vaginosis, Bacterial* / epidemiology