A perspective current and past modes of inhalation therapy

Microb Biotechnol. 2024 Feb;17(2):e14419. doi: 10.1111/1751-7915.14419.

Abstract

Inhalation is the preferred route of delivery for anti-asthma and chronic obstructive pulmonary disease (COPD) drugs. The use of this route has demonstrated efficacy in these and other conditions, it offers rapid onset of action, and is associated with minimal systemic exposure, thereby reducing the risk of adverse effects. Therefore, the current brief covers an interesting collection of inhaler action modes, shedding light on their molecular mechanisms and clinical applications for anti-asthma, COPD and antibacterial inhalation therapy. Hence, not only enriches our understanding of inhalation therapy molecular intricacies but also provides a comprehensive overview of the evolving landscape in clinical and antibacterial inhalation therapy. In doing so, it underscores the pivotal role of microbiology and biotechnology in advancing therapeutic approaches that harness the power of inhalation.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Administration, Inhalation*
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use
  • Humans
  • Nebulizers and Vaporizers*
  • Pulmonary Disease, Chronic Obstructive* / drug therapy

Substances

  • Anti-Bacterial Agents