Concentration of Tetrabromobisphenol-A in fish: systematic review and meta-analysis and probabilistic health risk assessment

Trias Mahmudiono; Yadolah Fakhri; Vahid Ranaei; Zahra Pilevar; Intissar Limam; Fatemeh Sahlabadi; Negin Rezaeiarshad; Marzieh Torabbeigi; Samaneh Jalali

doi:10.1515/reveh-2023-0157

Concentration of Tetrabromobisphenol-A in fish: systematic review and meta-analysis and probabilistic health risk assessment

Rev Environ Health. 2024 Feb 23. doi: 10.1515/reveh-2023-0157. Online ahead of print.

Authors

Trias Mahmudiono¹, Yadolah Fakhri², Vahid Ranaei³, Zahra Pilevar³, Intissar Limam⁴, Fatemeh Sahlabadi⁵, Negin Rezaeiarshad⁶, Marzieh Torabbeigi⁶, Samaneh Jalali⁶

Affiliations

¹ Department of Nutrition, Faculty of Public Health, 148005 Universitas Airlangga , Surabaya, Indonesia.
² Food Health Research Center, 14656 Hormozgan University of Medical Sciences , Bandar Abbas, Iran.
³ School of Health, 48412 Arak University of Medical Sciences , Arak, Iran.
⁴ Laboratory of Materials, Treatment and Analysis, National Institute of Research and Physicochemical Analysis, Biotechpole Sidi-Thabet, and High School for Science and Health Techniques of Tunis, University of Tunis El Manar, Tunis, Tunisia.
⁵ Department of Environmental Health Engineering, School of Health, Social Determinants of Health Research Center, 125609 Birjand University of Medical Sciences , Birjand, Iran.
⁶ Department of Environmental Health Engineering, School of Public Health and Safety, 556492 Shahid Beheshti University of Medical Sciences , Tehran, Iran.

PMID: 38386608
DOI: 10.1515/reveh-2023-0157

Abstract

Tetrabromobisphenol A (TBBP-A) is an emerging pollutant that enters water resources and affects various marine organisms, such as fish. Consequently, numerous studies globally investigated TBBP-A concentrations in fish fillets of the current study were meta-analyze concentration of TBBP-A in fish fillets and estimate the associated health risks for consumers. The search encompassed international databases, including Science Direct, PubMed, Scopus, Embase, and Web of Science from January 1, 2005, to July 20, 2023. The ranking of countries based on the pooled (Mean) concentration of TBBP-A in fish was as follows: China (1.157 µg/kg-ww) > Czech Republic (1.027 µg/kg-ww) > France (0.500 µg/kg-ww) ∼ Switzerland (0.500 µg/kg-ww) > Netherlands (0.405 µg/kg-ww) > Germany (0.33 µg/kg-ww) > Sweden (0.165 µg/kg-ww)>UK (0.078 µg/kg-ww) > Belgium (0.065 µg/kg-ww) > South Korea (0.013 µg/kg-ww) ∼ Japan (0.013 µg/kg-ww) > Ireland (0.005 µg/kg-ww). The risk assessment showed that the carcinogenic and non-carcinogenic risks of TBBP-A in China and France are higher compared to other countries; however, within all countries, these risks were found to be within acceptable limits.

Keywords: TBBP-A; Tetrabromobisphenol A; emerging contaminants; food safety; marine food; meta-analysis.

Publication types

Review