Objective: To review the research progress in the treatment of high-grade spondylolisthesis (HS), in order to provide a reference for clinical treatment decision-making.
Methods: The literature related to the treatment of HS at home and abroad in recent years was widely reviewed. The methods of conservative treatment, in situ fusion, and spondylolisthesis reduction were analyzed and summarized.
Results: Surgical treatment is the main treatment of HS, but which method is the best is still controversial. The advantages, disadvantages, and applicability of various operations are also different, so individualized analysis is needed in clinic.
Conclusion: The treatment plan of HS needs to be considered comprehensively according to the individual condition of the patient. It will be an important research direction to further compare the existing treatment methods and develop more safe and effective new technology.
目的: 对重度腰椎滑脱（high-grade spondylolisthesis，HS）的治疗进展进行综述，以期为临床治疗决策提供参考。.
方法: 广泛查阅国内外近年来HS治疗的相关文献，对保守治疗、原位融合、滑脱复位等治疗方式进行分析和总结。.
结果: HS的治疗以手术为主，但对于最佳手术方式的选择存在很大争议，不同手术的优缺点和适用情况也不同，临床需要个体化分析。.
结论: HS治疗方式的选择需要根据患者个体情况综合考虑，进一步比较现有治疗方法及研发更加安全有效的新技术是重要研究方向。.
Keywords: High-grade spondylolisthesis; nerve injury; spondylolisthesis reduction; surgical treatment.