Volumetric analysis in primary and residual type B aortic dissection treated with stented-assisted balloon-induced intimal disruption and relamination (STABILISE) technique can predict aortic reintervention

Marco Ferraresi; Alessandro Carlo Luigi Molinari; Maria Katsarou; Giovanni Rossi

doi:10.1016/j.jvs.2024.02.017

Volumetric analysis in primary and residual type B aortic dissection treated with stented-assisted balloon-induced intimal disruption and relamination (STABILISE) technique can predict aortic reintervention

J Vasc Surg. 2024 Feb 19:S0741-5214(24)00394-X. doi: 10.1016/j.jvs.2024.02.017. Online ahead of print.

Authors

Marco Ferraresi¹, Alessandro Carlo Luigi Molinari², Maria Katsarou², Giovanni Rossi²

Affiliations

¹ Division of Vascular Surgery, Cardio-Thoraco-Vascular Department, A. Manzoni Hospital, Lecco, Italy. Electronic address: marco.ferraresi7@gmail.com.
² Division of Vascular Surgery, Cardio-Thoraco-Vascular Department, A. Manzoni Hospital, Lecco, Italy.

PMID: 38382641
DOI: 10.1016/j.jvs.2024.02.017

Abstract

Objective: The aim of this study was to investigate the mid-term results of stented-assisted balloon-induced intimal disruption and relamination (STABILISE) in patients with aortic dissection with the implementation of volumetric analysis.

Methods: This was a single-center retrospective analysis of prospectively collected data. From May 2017 to September 2022, 42 patients underwent STABILISE for acute complicated or subacute high-risk aortic dissection. STABILISE was completed with distal extended endovascular aortic repair in 24 patients. A computed tomography scan was performed at baseline, before hospital discharge, and at 1, 3, and 5 years. Perfused total aortic, true lumen, and false lumen volumes were assessed for thoracic, visceral, and aorto-iliac segment. The ratio between false lumen and total volume was named perfusion dissection index (PDI). Complete remodeling was defined as PDI = 0, and positive remodeling as PDI ≤0.1.

Results: Technical success was 97.6%. No 30-day deaths, spinal cord injuries, or retrograde dissections were observed. Mean follow-up was 44 ± 19.4 months. Thoracic diameter was lower at last available computed tomography scan (36.7 vs 33.0 mm; P = .01). Aortic growth >5 mm was observed in 9.5% of the patients. Thoracic and visceral aortic complete remodeling were 92.8% and 83.3%, respectively, with no difference between acute and subacute group. Distal extended endovascular aortic repair significantly increased complete remodeling in the aorto-iliac segment, compared with STABILISE alone (69.6% vs 21.4%; P < .001). Freedom from vascular reinterventions at 3 years was 83.1% (95% confidence interval, 71.5%-96.6%). Total PDI ≤0.1 at first postoperative control was a predictor of vascular reinterventions (P < .0001).

Conclusions: STABILISE is a safe and feasible technique associated with high mid-term rates of complete remodeling in the thoracic and visceral aorta. Volumetric analysis allows the quantification of aortic remodeling and represents a predictor of aortic reinterventions.

Keywords: Aorta; Aortic dissection; Aortic remodeling; Endovascular; STABILISE; Volumetric analysis.