FLG Knockdown-Related Skin-Lung Crosstalk Biologically Underpins a Filaggrin-Related Childhood Asthma Subtype

J Invest Dermatol. 2024 May;144(5):921-923. doi: 10.1016/j.jid.2024.01.008. Epub 2024 Feb 17.

Authors

Somnath Mukhopadhyay¹, Sara J Brown²

Affiliations

¹ Department of Clinical and Experimental Medicine, Brighton and Sussex Medical School, Brighton, United Kingdom. Electronic address: S.Mukhopadhyay@bsms.ac.uk.
² Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburg, United Kingdom.

PMID: 38372679
DOI: 10.1016/j.jid.2024.01.008

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Asthma* / genetics
Asthma* / metabolism
Child
Female
Filaggrin Proteins*
Gene Knockdown Techniques
Humans
Intermediate Filament Proteins* / genetics
Intermediate Filament Proteins* / metabolism
Lung
Male
Skin* / metabolism
Skin* / pathology

Substances

Filaggrin Proteins
FLG protein, human
Intermediate Filament Proteins