Characterization of the novel HLA-DRB1*16:76 allele in a Chinese individual

HLA. 2024 Feb;103(2):e15395. doi: 10.1111/tan.15395.

Zhixiang Ren¹, Pei-Heng Li², Qing Hao¹, Heng Xu^{1

3}, Yun-Ying Shi⁴

¹ State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
² Division of Thyroid and Parathyroid Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
³ Department of Laboratory Medicine/Research Centre of Clinical Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
⁴ Department of Nephrology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Abstract

The HLA-DRB1*16:76 allele differs from HLA-DRB1*16:02:01 by one nucleotide substitution (A > G) at position 37 in exon 1.

Keywords: HLA-DRB1*16:76; novel allele; sequencing-based typing.