Abstract
After a brief recall of male sexual differentiation, main features of different etiopathogenetic forms conditioning male pseudohermaphroditism (MPSH) are considered. Procedures for an early and exact identification are illustrated in order to formulate an appropriate prognosis. Hormonal treatment and corrective surgery are discussed; in case of severe malformations, a gender reassignment may be evaluated.
MeSH terms
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3-Oxo-5-alpha-Steroid 4-Dehydrogenase / deficiency
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Disorders of Sex Development* / classification
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Disorders of Sex Development* / enzymology
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Disorders of Sex Development* / metabolism
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Disorders of Sex Development* / therapy
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Genotype
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Gonadal Steroid Hormones / metabolism
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Humans
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Male
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Orchiectomy
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Receptors, Androgen / metabolism
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Sex Differentiation
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Testicular Diseases / metabolism
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Testosterone / biosynthesis
Substances
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Gonadal Steroid Hormones
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Receptors, Androgen
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Testosterone
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3-Oxo-5-alpha-Steroid 4-Dehydrogenase