Language and executive function of clinical stage-1 HIV patients in an industrial scenario: Extent and implication

Ind Psychiatry J. 2023 Nov;32(Suppl 1):S147-S150. doi: 10.4103/ipj.ipj_232_23. Epub 2023 Nov 30.

Abstract

Background: Asymptomatic and mild form of the neurocognitive disorder in individuals with human immunodeficiency virus infection is still prevalent and a chief problem worldwide although the severity of the neurocognitive complications is decreasing after the introduction of combined highly active antiretroviral therapy.

Aim: To study language and executive dysfunction of HIV patients in Clinical Stage 1 in an industrial scenario in Western Maharashtra as compared to healthy controls.

Material and methods: The Wisconsin card sorting test and Addenbrooke cognitive scale were done to check for executive function and language, respectively, and compared to age- and gender-matched HIV-negative controls.

Results: Both the results of the WCST and Addenbrooke cognitive scale showed a decline in scores in the cases as compared to the controls overall. The distribution of cases as per the gender showed no significant difference, whereas there was a significant difference as per the age.

Conclusion: In asymptomatic HIV patients, there is a decline in executive function and language as compared to the healthy controls. As most of the individuals were employed, there is a need to assess their neurocognitive function regularly as the progress of the illness can be monitored and cognitive training can be advised in these HIV-positive patients, which will not only benefit the individuals but the industrial sector in the long run as well.

Keywords: Executive function; HIV; language; stage 1.