One-year Outcomes of Ultrathin Descemet Stripping Automated Endothelial Keratoplasty Combined with Cataract Surgery in the Korean Population

Korean J Ophthalmol. 2024 Apr;38(2):105-112. doi: 10.3341/kjo.2023.0101. Epub 2024 Feb 14.

Abstract

Purpose: To evaluate the refractive outcomes after ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) combined with phacoemulsification and intraocular lens implantation (triple procedure) in the South Korean population.

Methods: This retrospective observational study included 37 eyes of 36 patients who underwent the UT-DSAEK triple procedure between 2012 and 2021 in a single tertiary hospital. Preoperative and postoperative refractive outcomes and endothelial parameters at 1, 3, 6, and 12 months were observed.

Results: At the final postoperative 12-month period, the average best-corrected visual acuity was 0.4 ± 0.5 in logarithm of the minimum angle of resolution. The mean endothelial cell density at 12 months was 1,841.92 ± 731.24 cells/mm2, indicating no significant endothelial cell loss compared to the baseline (p = 0.128). The mean postoperative central corneal thickness at 12 months was 597.41 ± 86.26 μm. The postoperative mean absolute error at 12 months was 0.96 ± 0.89 diopters (D) and mean error was 0.89 ± 0.97 D.

Conclusions: The results of our South Korean cohort study on UT-DSAEK triple surgery showed favorable and safe outcomes. Regardless of graft thickness, it should be noted that a hyperopic shift of 1.00 to 2.00 D needs to be considered in the case of UT-DSAEK triple surgery.

Keywords: Corneal transplantation; Descemet stripping automated endothelial keratoplasty (DSAEK); Transplantation; Ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK).

Publication types

  • Observational Study

MeSH terms

  • Cataract*
  • Cohort Studies
  • Corneal Transplantation*
  • Descemet Stripping Endothelial Keratoplasty* / methods
  • Endothelium, Corneal / transplantation
  • Fuchs' Endothelial Dystrophy* / surgery
  • Humans
  • Refraction, Ocular
  • Retrospective Studies
  • Visual Acuity