Revisiting the Multifaceted Roles of Bacteriocins : The Multifaceted Roles of Bacteriocins

Microb Ecol. 2024 Feb 14;87(1):41. doi: 10.1007/s00248-024-02357-4.

Abstract

Bacteriocins are gene-encoded antimicrobial peptides produced by bacteria. These peptides are heterogeneous in terms of structure, antimicrobial activities, biosynthetic clusters, and regulatory mechanisms. Bacteriocins are widespread in nature and may contribute to microbial diversity due to their capacity to target specific bacteria. Primarily studied as food preservatives and therapeutic agents, their function in natural settings is however less known. This review emphasizes the ecological significance of bacteriocins as multifunctional peptides by exploring bacteriocin distribution, mobility, and their impact on bacterial population dynamics and biofilms.

Keywords: Bacterial communication; Bacteriocin; Biofilm; Horizontal gene transfer; Microbial competition; Quorum sensing.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Bacteria
  • Bacteriocins* / pharmacology
  • Biofilms
  • Peptides

Substances

  • Bacteriocins
  • Peptides
  • Anti-Bacterial Agents