The role of phospholipids in drug delivery formulations - Recent advances presented at the Researcher's Day 2023 Conference of the Phospholipid Research Center Heidelberg

Eur J Pharm Biopharm. 2024 Apr:197:114215. doi: 10.1016/j.ejpb.2024.114215. Epub 2024 Feb 11.

Abstract

This Focus on Meetings contribution summarizes recent advances in the research on phospholipids and their applications for drug delivery and analytical purposes that have been presented at the hybrid Researcher's Day 2023 Conference of the Phospholipid Research Center (PRC), held on July 3-5, 2023, in Bad Dürkheim, Germany. The PRC is a non-profit organization focused on expanding and sharing scientific and technological knowledge of phospholipids in pharmaceutical and other applications. This is accomplished by, e.g., funding doctoral and postdoctoral research projects. The progress made with these projects is presented at the Researcher's Day Conference every two years. Four main topics were presented and discussed in various lectures: (1) formulation of phospholipid-based nanocarriers, (2) therapeutic applications of phospholipids and phospholipid-based nanocarriers, (3) phospholipids as excipients in oral, dermal, and parenteral dosage forms, and (4) interactions of phospholipids and phospholipid-based vesicles in biological environment and their use as analytical platforms.

Keywords: Dermal; Drug delivery; Excipients; Lecithin; Lipid nanoparticles; Oral; Parenteral; Phospholipid-based nanocarriers; Phospholipids.

MeSH terms

  • Drug Carriers
  • Drug Delivery Systems*
  • Excipients
  • Pharmaceutical Preparations
  • Phospholipids*

Substances

  • Phospholipids
  • Pharmaceutical Preparations
  • Excipients
  • Drug Carriers