A Predictive Strategy for Nonsurgical Management of Pancreatic Stones

Pancreas. 2024 Apr 1;53(4):e338-e342. doi: 10.1097/MPA.0000000000002310. Epub 2024 Feb 12.

Abstract

Objectives: We set out to predict whether nonsurgical treatment is likely to succeed in removing pancreatic stones in a given patient and also to determine an optimal maximal number of extracorporeal shock wave lithotripsy (ESWL) sessions for treatment of pancreatolithiasis in that patient.

Materials and methods: We ascertained the number of ESWL sessions for each of 164 patients undergoing that treatment for pancreatolithiasis between 1992 and 2020. Median follow-up duration was 31 months (range, 0-239), median age was 58 years (22-83), and the male to female ratio was 5.1:1.0. Patients were divided into 2 groups based upon an optimal maximal number of ESWL sessions determined by receiver operating characteristic analysis.

Results: Total stone clearance was achieved in 130 of 164 patients (79%). The median number of ESWL sessions was 3 (1-61). Receiver operating characteristic analysis determined 7 to be the optimal maximal number of sessions. Complete clearance was more frequent (87%) among the 131 patients requiring 7 or fewer ESWL sessions than among the 33 undergoing more (48%, P < 0.001). Seventeen patients (52%) undergoing 8 or more sessions still had residual stones.

Conclusions: If any pancreatic stones persist after 7 ESWL sessions, we recommend transition to medical or surgical treatments.

MeSH terms

  • Calculi* / therapy
  • Female
  • Humans
  • Lithotripsy*
  • Male
  • Middle Aged
  • Pancreatic Diseases* / diagnosis
  • Pancreatic Diseases* / therapy
  • Treatment Outcome