A supervised machine learning model for identifying predictive factors for recommending head and neck cancer surgery

Head Neck. 2024 May;46(5):1001-1008. doi: 10.1002/hed.27674. Epub 2024 Feb 12.

Abstract

Background: New patient referrals are often processed by practice coordinators with little-to-no medical background. Treatment delays due to incorrect referral processing, however, have detrimental consequences. Identifying variables that are associated with a higher likelihood of surgical oncological resection may improve patient referral processing and expedite the time to treatment. The study objective is to develop a supervised machine learning (ML) platform that identifies relevant variables associated with head and neck surgical resection.

Methods: A retrospective cohort study was conducted on 64 222 patient datapoints from the SEER database.

Results: The random forest ML model correctly classified patients who were offered head and neck surgery with an 81% accuracy rate. The sensitivity and specificity rates were 86% and 71%. The positive and negative predictive values were 85% and 73%.

Conclusions: ML modeling accurately predicts head and neck cancer surgery recommendations based on patient and cancer information from a large population-based dataset. ML adjuncts for referral processing may decrease the time to treatment for patients with cancer.

Keywords: carcinoma; decision tree; head and neck cancer; machine learning; random forest; surgery.

MeSH terms

  • Head and Neck Neoplasms* / surgery
  • Humans
  • Neck
  • Predictive Value of Tests
  • Retrospective Studies
  • Supervised Machine Learning*