Nationwide epidemiological survey of polyarteritis nodosa in Japan in 2020

Mai Kawazoe; Toshihiro Nanki; Keigo Saeki; Hideki Ishikawa; Yoshikazu Nakamura; Soko Kawashima; Shuichi Ito; Masanari Kodera; Naoko Konda; Shinya Kaname; Masayoshi Harigai

doi:10.1093/mr/roae010

Nationwide epidemiological survey of polyarteritis nodosa in Japan in 2020

Mod Rheumatol. 2024 Feb 7:roae010. doi: 10.1093/mr/roae010. Online ahead of print.

Authors

Affiliations

¹ Division of Rheumatology, Department of Internal Medicine, School of Medicine, Faculty of Medicine, Toho University, Tokyo, Japan.
² Department of Epidemiology, Nara University School of Medicine, Nara, Japan.
³ Department of Molecular-Targeting Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
⁴ Department of Public Health, Jichi Medical University, Tochigi, Japan.
⁵ Department of Nephrology and Rheumatology, Kyorin University School of Medicine, Tokyo, Japan.
⁶ Department of Pediatrics, Graduate School of Medicine, Yokohama City University, Yokohama, Japan.
⁷ Department of Dermatology, Japan Community Health Care Organization Chukyo Hospital, Aichi, Japan.
⁸ Division of Rheumatology, Department of Internal Medicine, Tokyo Women's Medical University School of Medicine, Tokyo, Japan.

PMID: 38343272
DOI: 10.1093/mr/roae010

Abstract

Polyarteritis nodosa (PAN) is a systemic necrotizing vasculitis that predominantly affects medium-sized arteries. With advances in our understanding of the pathogenesis and classification of vasculitis, PAN and microscopic polyangiitis (MPA), a disease of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV), were separated from the group of diseases previously diagnosed as periarteritis nodosa (PN) at the Chapel Hill Consensus Conference (CHCC) in 1994 (1).

Keywords: Japan; epidemiology; polyarteritis nodosa; prevalence; systemic vasculitis.