The Amager Project IV: suicidal behavior and aftercare: real world data (RWD) from a prospective observational project

Nord J Psychiatry. 2024 May;78(4):267-271. doi: 10.1080/08039488.2024.2315163. Epub 2024 Feb 10.

Abstract

Background: In an RCT study, OPAC (outreach, problem solving, adherence, continuity) approach to aftercare after suicide attempts had an effect. The present study used the OPAC method in a clinical setting on Amager Copenhagen to patients after suicide attempt (Group 1) and patients with suicide ideation (Group 2) in a real-world data (RWD) study.

Aim: To study whether the OPAC method could provide real world evidence (RWE) for results from the RCT study and long-time prospects.

Method: This RWD study included 506 patients and followed them for 5 years. Kaplan-Meyer showed 5 years results. Risk factors for 5 years were calculated.

Results: 206 males (mean age 37.9) and 300 females (mean age 35.2) participated. A decline in survival accelerated after 3 years. After a 2-year follow-up, Group 1 had an attempted suicide rate of 12,2% and Group 2 5,4%. After 5 years the numbers were 18% and 10%. There were 3 completed suicides. Risk factors were: earlier suicide attempts, one or both parents or they themselves were alcohol/drug abusers, and a poor social network. Group 1 showed the same result as the intervention group in our earlier RCT study. Group 2 did better. Both groups did better than the control group from our RCT study.

Conclusion: The OPAC effect was translated into the daily clinic. Risk factors were previous suicide attempts, alcohol and drug abuse and poor social networks. More specific therapy is needed for some patients to prevent relapse. Focus on enhancing a sense of belongingness and/or treating substance abuse.

Keywords: RCT study; Suicide; prevention; real-world data (RWD); suicide risk factors.

Publication types

  • Observational Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aftercare*
  • Denmark / epidemiology
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Risk Factors
  • Substance-Related Disorders / epidemiology
  • Substance-Related Disorders / psychology
  • Suicidal Ideation*
  • Suicide, Attempted* / psychology
  • Suicide, Attempted* / statistics & numerical data
  • Suicide, Completed / statistics & numerical data