Manifestations and management of Sjögren's disease

Mehrnaz Maleki-Fischbach; Liudmila Kastsianok; Matthew Koslow; Edward D Chan

doi:10.1186/s13075-024-03262-4

Manifestations and management of Sjögren's disease

Arthritis Res Ther. 2024 Feb 8;26(1):43. doi: 10.1186/s13075-024-03262-4.

Authors

Mehrnaz Maleki-Fischbach¹, Liudmila Kastsianok², Matthew Koslow³, Edward D Chan^{3

4}

Affiliations

¹ Division of Rheumatology and Department of Medicine, National Jewish Health, 1400 Jackson Street, Denver, CO, 80206, USA. MalekiM@NJHealth.org.
² Division of Rheumatology and Department of Medicine, National Jewish Health, 1400 Jackson Street, Denver, CO, 80206, USA.
³ Division of Pulmonary, Critical Care and Sleep Medicine, National Jewish Health, Denver, CO, USA.
⁴ Pulmonary Section, Rocky Mountain Regional Veterans Affairs Medical Center Aurora, Aurora, CO, USA.

Abstract

Sjögren's disease is a heterogeneous autoimmune disorder that may be associated with systemic manifestations such as pulmonary or articular involvement. Systemic complications have prognostic implications and need to be identified and managed in a timely manner. Treatment should be tailored to the type and severity of organ involvement, ideally based on multidisciplinary evaluation.

Keywords: Pulmonary fibrosis; Sjögren’s syndrome; Systemic manifestations; Treatment.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Autoimmune Diseases* / complications
Humans
Sjogren's Syndrome* / complications
Sjogren's Syndrome* / diagnosis
Sjogren's Syndrome* / therapy