Critical Illness-Related Corticosteroid Insufficiency (CIRCI) After Pediatric Cardiac Surgery

World J Pediatr Congenit Heart Surg. 2024 Mar;15(2):209-214. doi: 10.1177/21501351231221455. Epub 2024 Feb 6.

Abstract

Although current studies do not support the routine use of corticosteroids after cardiopulmonary bypass in pediatric patients, there is incomplete understanding of the potential hemodynamic contribution of postoperative critical illness-related corticosteroid insufficiency in the intensive care unit. By reviewing the available studies and underlying pathophysiology of these phenomena in critically ill neonates, we can identify a subset of patients that may benefit from optimal diagnosis and treatment of receiving postoperative steroids. A suggested algorithm used at our institution is provided as a guideline for treatment of this high-risk population.

Keywords: cardiopulmonary bypass; circulatory hemodynamics; congenital heart disease; congenital heart surgery; intensive care; neonate; postoperative care.

Publication types

  • Review

MeSH terms

  • Adrenal Cortex Hormones
  • Adrenal Insufficiency* / diagnosis
  • Adrenal Insufficiency* / epidemiology
  • Cardiac Surgical Procedures*
  • Child
  • Critical Illness
  • Humans
  • Infant, Newborn
  • Intensive Care Units

Substances

  • Adrenal Cortex Hormones