Caffeine and Less Invasive Surfactant Administration for Respiratory Distress Syndrome of the Newborn

NEJM Evid. 2023 Dec;2(12):EVIDoa2300183. doi: 10.1056/EVIDoa2300183. Epub 2023 Nov 21.

Abstract

Caffeine and Less Invasive Surfactant Administration for RDSPreterm infants with respiratory distress syndrome may benefit from the use of less invasive surfactant administration or continuous positive airway pressure to avoid intubation. The authors compare the two methods, with the additional use of caffeine in both groups.

MeSH terms

  • Caffeine / therapeutic use
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Lipoproteins / therapeutic use
  • Pulmonary Surfactants* / therapeutic use
  • Respiratory Distress Syndrome, Newborn* / drug therapy
  • Surface-Active Agents / therapeutic use

Substances

  • Caffeine
  • Surface-Active Agents
  • Pulmonary Surfactants
  • Lipoproteins