Environmental factors and their impact on chronic pain development and maintenance

Phys Life Rev. 2024 Mar:48:176-197. doi: 10.1016/j.plrev.2024.01.007. Epub 2024 Jan 26.

Abstract

It is more than recognized and accepted that the environment affects the physiological responses of all living things, from bacteria to superior vertebrates, constituting an important factor in the evolution of all species. Environmental influences range from natural processes such as sunlight, seasons of the year, and rest to complex processes like stress and other mood disorders, infections, and air pollution, being all of them influenced by how each creature deals with them. In this chapter, it will be discussed how some of the environmental elements affect directly or indirectly neuropathic pain, a type of chronic pain caused by a lesion or disease of the somatosensory nervous system. For that, it was considered the edge of knowledge in translational research, thus including data from human and experimental animals as well as the applicability of such findings.

Keywords: Ambient influence; Chronic pain; Environment; Neuropathic pain; Psychosocial factors.

Publication types

  • Review

MeSH terms

  • Air Pollution*
  • Animals
  • Chronic Pain* / complications
  • Humans
  • Neuralgia* / etiology
  • Seasons