Computed Tomography Imaging of the Larynx for Diagnosis of Vocal Cord Dysfunction

Joo H Koh; Laurence E Ruane; Debra Phyland; Kais Hamza; Risa Fukusho; Elizabeth Leahy; Adriana Avram; Grace Yap; Kenneth K Lau; Martin I MacDonald; Paul Leong; Malcolm Baxter; Philip G Bardin

doi:10.1056/EVIDoa2200183

Computed Tomography Imaging of the Larynx for Diagnosis of Vocal Cord Dysfunction

NEJM Evid. 2023 Jan;2(1):EVIDoa2200183. doi: 10.1056/EVIDoa2200183. Epub 2022 Dec 22.

Authors

Joo H Koh^{1

2}, Laurence E Ruane^{1

3}, Debra Phyland², Kais Hamza⁴, Risa Fukusho¹, Elizabeth Leahy¹, Adriana Avram¹, Grace Yap¹, Kenneth K Lau⁵, Martin I MacDonald^{1

3}, Paul Leong^{1

3}, Malcolm Baxter^{1

2}, Philip G Bardin^{1

3}

Affiliations

¹ Monash Lung Sleep Allergy & Immunology, Monash Health and University, Melbourne, Victoria, Australia.
² Ear, Nose, and Throat Surgery, Monash Health, Melbourne, Victoria, Australia.
³ Hudson Institute and School of Clinical Sciences, Monash University, Melbourne, Victoria, Australia.
⁴ School of Mathematical Sciences, Monash University, Melbourne, Victoria, Australia.
⁵ Diagnostic Imaging, Monash Health and University, Melbourne, Victoria, Australia.

PMID: 38320086
DOI: 10.1056/EVIDoa2200183

Abstract

Larynx CT for Vocal Cord Dysfunction DiagnosisThis study compared VCD diagnosis using CT imaging of the larynx with laryngoscopy (diagnostic standard). In one, CT imaging and laryngoscopy were performed on the same day; in the other, diagnostic studies were 4 to 6 weeks apart. A negative CT imaging result had a negative predictive value for VCD greater than 80% when positive population prevalence was 30%.

MeSH terms

Humans
Laryngoscopy
Larynx*
Tomography, X-Ray Computed
Vocal Cord Dysfunction* / diagnosis
Vocal Cords