Resolution of Radiculopathy Following Indirect Versus Direct Decompression in Single Level Lumbar Fusion

Global Spine J. 2024 Feb 5:21925682241230926. doi: 10.1177/21925682241230926. Online ahead of print.

Abstract

Study design: Retrospective analysis.

Objectives: To evaluate resolution of radiculopathy in one-level lumbar fusion with indirect or direct decompression techniques.

Methods: Patients ≥18 years of age with preoperative radiculopathy undergoing single-level lumbar fusion with up to 2-year follow-up were grouped by indirect and direct decompression. Direct decompression (DD) group included ALIF and LLIF with posterior DD procedure as well as all TLIF. Indirect decompression (ID) group included ALIF and LLIF without posterior DD procedure. Propensity score matching was used to control for intergroup differences in age. Intergroup outcomes were compared using means comparison tests. Logistic regressions were used to correlate decompression type with symptom resolution over time. Significance set at P < .05.

Results: 116 patients were included: 58 direct decompression (DD) (mean 53.9y, 67.2% female) and 58 indirect decompression (ID) (mean 54.6y, 61.4% female). DD patients experienced greater blood loss than ID. Additionally, DD patients were 4.7 times more likely than ID patients to experience full resolution of radiculopathy at 3 months post-op. By 6 months, DD patients demonstrated larger reductions in VAS score. With regard to motor function, DD patients had improved motor score associated with the L5 dermatome at 6 months relative to ID patients.

Conclusions: Direct decompression was associated with greater resolution of radiculopathy in the near post-operative term, with no differences at long term follow-up when compared with indirect decompression. In particularly debilitated patients, these findings may influence surgeons to perform a direct decompression to achieve more rapid resolution of radiculopathy symptoms.

Keywords: academic; anterior lumbar interbody fusion; decompression; direct; fusion; indirect; interbody; lateral lumbar interbody fusion; lumbar; one-level; retrospective; single-level; surgery; transforaminal; transforaminal lumbar interbody fusion.