One-step hydrothermal synthesis of CuS/MoS2 composite for use as an electrochemical non-enzymatic glucose sensor

Krishna Prasad Sharma; Miyeon Shin; Ganesh Prasad Awasthi; Soonhwan Cho; Changho Yu

doi:10.1016/j.heliyon.2023.e23721

One-step hydrothermal synthesis of CuS/MoS₂ composite for use as an electrochemical non-enzymatic glucose sensor

Heliyon. 2023 Dec 15;10(2):e23721. doi: 10.1016/j.heliyon.2023.e23721. eCollection 2024 Jan 30.

Authors

Krishna Prasad Sharma¹, Miyeon Shin¹, Ganesh Prasad Awasthi², Soonhwan Cho³, Changho Yu^{1

2}

Affiliations

¹ Department of Energy Storage/Conversion Engineering (BK21 FOUR), Jeonbuk National University, Jeonju, Jeollabuk-do, 54896, Republic of Korea.
² Division of Convergence Technology Engineering, Jeonbuk National University, Jeonju, Jeollabuk-do, 54896, Republic of Korea.
³ ENPLUS Co., LTD, 167 Jayumuyeok-gil, Baeksan-myeon, Gimje-si, 54352, Republic of Korea.

Abstract

Early diagnosis may be crucial for the prevention of chronic diabetes mellitus. For that herein, we prepared a CuS/MoS₂ composite for a non-enzymatic glucose sensor through a one-step hydrothermal method owing to the synergetic effect of CuS/MoS₂. The surface morphology of CuS/MoS₂ was studied by Field Emission Scanning Electron Microscopy (FESEM) and Cs-corrected Scanning Transmission Electron Microscopy (Cs-STEM). The crystallinity and surface composition of CuS/MoS₂ were analyzed by X-ray Diffraction (XRD) and X-ray Photoelectron Spectroscopy (XPS) respectively. The working electrode was prepared from CuS/MoS₂ electrocatalyst, and for that dispersed solution of electrocatalyst was used to fabricate the material-loaded glassy carbon electrode (GC). CuS/MoS₂ composite shows the viability of electrocatalyst to oxidize glucose in an alkaline solution with sensitivity and detection limit of 252.71 μA mM^-1 cm^-2 and 1.52 μM respectively. The proposed glucose sensor showed reasonable stability and potential selectivity during electrochemical analysis. Accordingly, the CuS/MoS₂ composite has potential as a viable material for glucose sensing in diluted human serum.

Keywords: Copper sulfide; Hydrothermal; Molybdenum disulfide; Selectivity; Sensitivity.