Cardiac Mass and Cerebrovascular Accident as Primary Manifestations of Churg-Strauss Syndrome

Arch Iran Med. 2023 Nov 1;26(11):662-664. doi: 10.34172/aim.2023.97.

Abstract

Churg-Strauss syndrome (CSS), recently named eosinophilic granulomatosis with polyangiitis (EGPA), is a rare form of systemic vasculitis with extravascular granulomas occurring in patients with asthma and tissue eosinophilia. We represent a large left ventricular granuloma, confirmed by histopathologic evaluation, detected as a ventricular mass by echocardiography in a 45-year-old asthmatic male who was admitted for a cerebrovascular accident. Paraclinical and histopathologic findings confirmed the diagnosis of EGPA. As cardiac involvement in patients with EGPA is associated with poor prognosis, routine echocardiographic evaluation of these patients is suggested.

Keywords: Cardiac mass; Churg-Strauss syndrome; Eosinophilia; Granuloma; Vasculitis.

MeSH terms

  • Asthma* / complications
  • Churg-Strauss Syndrome* / complications
  • Churg-Strauss Syndrome* / diagnosis
  • Eosinophils
  • Granulomatosis with Polyangiitis* / complications
  • Humans
  • Male
  • Middle Aged
  • Stroke* / complications
  • Stroke* / etiology