IgG4-related mastitis managed without excision or steroid therapy

Hirokazu Matsushima; Masayuki Kikuchi; Rika Miyabe; Sota Yamaguchi; Hidenori Kita; Junko Kobayashi; Takashi Ando; Koji Atsuta; Takayoshi Soga; Tsunehiro Shintani

doi:10.1186/s40792-024-01826-9

IgG4-related mastitis managed without excision or steroid therapy

Surg Case Rep. 2024 Feb 2;10(1):32. doi: 10.1186/s40792-024-01826-9.

Affiliations

¹ Department of Surgery, Japanese Red Cross Shizuoka Hospital, 8-2, Ottemachi, Aoi-Ku, Shizuoka, Shizuoka, 420-0853, Japan.
² Department of Surgery, Japanese Red Cross Shizuoka Hospital, 8-2, Ottemachi, Aoi-Ku, Shizuoka, Shizuoka, 420-0853, Japan. kikuchimasayuki1224@hotmail.co.jp.
³ Tosen Clinic, 1-20, Gohukucho, Aoi-Ku, Shizuoka, Shizuoka, 420-0031, Japan.
⁴ Department of Rheumatology, Japanese Red Cross Shizuoka Hospital, 8-2, Ottemachi, Aoi-Ku, Shizuoka, Shizuoka, 420-0853, Japan.

Abstract

IgG4-related mastitis is an extremely rare IgG4-related sclerosing disease involving the breast that must be differentiated from breast cancer. There is currently no consensus regarding the optimal treatment strategies. Here, we report a case of IgG4-related mastitis followed up without excision or steroid therapy. Although the association between IgG4-related mastitis and breast cancer remains unclear, regular follow-up imaging and measurement of serum concentrations of disease activity markers may allow for follow-up without excision or steroid therapy.

Keywords: Breast mass; IgG4-related mastitis; IgG4-related sclerosing disease.

Publication types

Letter