Positive outcomes with neoadjuvant chemotherapy in the management of colovesical fistula in cancer: a case report and literature review

Song Tang; Xinjun Li; Donghua Guo; Fan Zhuo

doi:10.3389/fphar.2023.1284316

Positive outcomes with neoadjuvant chemotherapy in the management of colovesical fistula in cancer: a case report and literature review

Front Pharmacol. 2024 Jan 15:14:1284316. doi: 10.3389/fphar.2023.1284316. eCollection 2023.

Authors

Song Tang¹, Xinjun Li², Donghua Guo³, Fan Zhuo¹

Affiliations

¹ Department of Gastrointestinal Surgery, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.
² Department of Oncological Surgery, Guangzhou Royallee Cancer Center, Guangzhou, Guangdong, China.
³ Medical Imaging Unit, Guangzhou Royallee Cancer Center, Guangzhou, Guangdong, China.

Abstract

Colovesical fistula (CVF) is usually developed from colonic diverticulitis, followed by tumor. Traditional surgery is usually completed in one or more stages. For complex cancerous CVF, radical resection is more difficult. We report a 62-year-old male patient diagnosed with sigmoid colon cancer combined with sigmoid vesical fistula. In the course of treatment, in addition to conventional surgery, neoadjuvant chemotherapy (NAC) was innovatively used. The sigmoid tumor and fistula were significantly shrunken. Radical surgery achieved negative margins.

Keywords: cancerous colovesical fistula; case report; neoadjuvant chemotherapy; sigmoid colon cancer; treatment.

Publication types

Case Reports

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the Medical Science and Technology Research Foundation of Guangdong Province (No. B2023361).