α-Umpolung/Michael Addition/Quaternization Tandem Reaction to provide α-Imido-β-phosphonium Propanoates with Broad Spectrum of Biological Activity

Chem Biodivers. 2024 Mar;21(3):e202302022. doi: 10.1002/cbdv.202302022. Epub 2024 Feb 21.

Abstract

This paper has been supported by the Kazan Federal University Strategic Academic Leadership Program ('PRIORITY-2030'). HRMS data were obtained in the CSF-SAC FRC KSC RAS by support of the State Assignment of the Federal Research Center "Kazan Scientific Center", Russian Academy of Sciences. A.D.V, conducted studies of anticancer activity with financial support form the government assignment for FRC Kazan Scientific Center of RAS.

Keywords: Anticancer activity; Human cancer cell lines; Phosphine catalysis; Phosphonium salt; α-addition.

MeSH terms

  • Chemical Phenomena
  • Humans
  • Propionates*

Substances

  • Propionates