Venous Thromboembolism and Associated Factors in Hospitalized Patients with COVID-19 at Addis Ababa COVID-19 Field Hospital, Ethiopia

Abel Teklit Haile; Robel Gemechu Haile; Esrom Hagos Gebrehiwot; Eden Workalemahu Abeje

doi:10.2147/IDR.S449401

Venous Thromboembolism and Associated Factors in Hospitalized Patients with COVID-19 at Addis Ababa COVID-19 Field Hospital, Ethiopia

Infect Drug Resist. 2024 Jan 26:17:305-317. doi: 10.2147/IDR.S449401. eCollection 2024.

Authors

Abel Teklit Haile^{1

2}, Robel Gemechu Haile^{1

2

3}, Esrom Hagos Gebrehiwot^{1

2

3}, Eden Workalemahu Abeje^{1

2

3}

Affiliations

¹ Research Department, Saint Peter Specialized Hospital, Addis Ababa, Ethiopia.
² Department of Internal Medicine, Wollo University, Dessie, Ethiopia.
³ School of Public Health, Gamby Medical and Business College, Addis Ababa, Ethiopia.

Abstract

Background: The association of COVID-19 with venous thromboembolism is of particular interest as there are reports that have associated thrombotic events with the pandemic. COVID-19 may predispose to venous thromboembolism. There is initial evidence suggesting that individuals with COVID-19 may be more prone to developing venous thromboembolism (VTE). This study aims to assess venous thromboembolism and associated factors in 19 patients admitted to Addis Ababa's field hospital for COVID-19.

Objective: To identify associated factors that affect the development of thromboembolism in patients admitted with the diagnosis of COVID-19.

Methods: To determine the risks of VTE patients, an institution-based case control research was conducted using SPSS version 26, multivariable binary logistic regression analysis was used.

Results: Significant factors associated with the development of VTE in COVID-19 patients included having a severe case (AOR = 0.38, 95% CI = 0.149-0.961), risk factors for VTE (AOR = 2.57, 95% CI = 1.18-5.33), diabetes (AOR = 3.745, 95% CI = 1.715-8.176), chest pain (AOR = 4.13, 95% CI = 1.89-9), stage 1 hypertension levels (AOR = 3.67, 95% CI = 1.37-9.836), and hospital anticoagulation (AOR = 11.78, 95% CI = 5.25-26.4).

Conclusion: The results of VTE in individuals with COVID-19 imply a direct association between severe COVID-19 and diabetes, having risk factors, hypertension, and hospital anticoagulation.

Keywords: Addis Ababa; COVID-19; Ethiopia; case control; logistic regression; venous thromboembolism.

Grants and funding

No grant from a public, private, or nonprofit organization was given for this research.