Hereditary Protein S Deficiency With an Extensive Femoral Artery Thrombosis

Noor Haslina Mohd Noor; Nurul Anis Che Anuar; Nur Ilyia Syazwani Saidin; Salfarina Iberahim; Abdul Hanan Abdullah

doi:10.7759/cureus.51355

Hereditary Protein S Deficiency With an Extensive Femoral Artery Thrombosis

Cureus. 2023 Dec 30;15(12):e51355. doi: 10.7759/cureus.51355. eCollection 2023 Dec.

Authors

Noor Haslina Mohd Noor¹, Nurul Anis Che Anuar¹, Nur Ilyia Syazwani Saidin¹, Salfarina Iberahim¹, Abdul Hanan Abdullah²

Affiliations

¹ Department of Hematology, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, MYS.
² Department of Internal Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, MYS.

Abstract

Protein S (PS) deficiency is widely recognized for its connection to venous thromboembolism risk. However, the relation between PS deficiency and arterial thrombotic events (ATEs) remains uncertain. Here, we report a patient who experienced an ATE with a family history of PS deficiency. We highlight an attention to the issues related to the management of arterial thrombotic events and discuss the potential use of antiplatelet therapy as a treatment option for a specific group of patients diagnosed with PS deficiency.

Keywords: atrial thrombosis; blood coagulation disorder; haemostasis; hereditary protein s deficiency; hereditary thrombophilia.

Publication types

Case Reports