Back to the Future: Dynamic Contrast-Enhanced Photon-Counting Detector CT for the Detection of Pituitary Adenoma in Cushing Disease

Ian T Mark; Jamie Van Gompel; Irina Bancos; Alex A Nagelschneider; Derek R Johnson; Girish Bathla; Ajay A Madhavan; Nikkole M Weber; Lifeng Yu

doi:10.3174/ajnr.A8171

Back to the Future: Dynamic Contrast-Enhanced Photon-Counting Detector CT for the Detection of Pituitary Adenoma in Cushing Disease

AJNR Am J Neuroradiol. 2024 Apr 11. doi: 10.3174/ajnr.A8171. Online ahead of print.

Authors

Ian T Mark¹, Jamie Van Gompel², Irina Bancos³, Alex A Nagelschneider⁴, Derek R Johnson⁴, Girish Bathla⁴, Ajay A Madhavan⁴, Nikkole M Weber⁴, Lifeng Yu⁴

Affiliations

¹ From the Department of Radiology (I.T.M. A.A.N., D.R.J., G.B., A.A.M., N.M.W., L.Y.), Mayo Clinic, Rochester, Minnesota Mark.Ian@mayo.edu.
² Department of Neurosurgery (J.V.G.), Mayo Clinic, Rochester, Minnesota.
³ Department of Endocrinology (I.B.), Mayo Clinic, Rochester, Minnesota.
⁴ From the Department of Radiology (I.T.M. A.A.N., D.R.J., G.B., A.A.M., N.M.W., L.Y.), Mayo Clinic, Rochester, Minnesota.

PMID: 38290737
DOI: 10.3174/ajnr.A8171

Abstract

Historically, MR imaging has been unable to detect a pituitary adenoma in up to one-half of patients with Cushing disease. This issue is problematic because the standard-of-care treatment is surgical resection, and its success is correlated with finding the tumor on imaging. Photon-counting detector CT is a recent advancement that has multiple benefits over conventional energy-integrating detector CT. We present the use of dynamic contrast-enhanced imaging using photon-counting detector CT for the detection of pituitary adenomas in patients with Cushing disease.