Rapid review of ventilator-induced diaphragm dysfunction

Respir Med. 2024 Mar:223:107541. doi: 10.1016/j.rmed.2024.107541. Epub 2024 Jan 28.

Abstract

Ventilator-induced diaphragm dysfunction is gaining increased recognition. Evidence of diaphragm weakness can manifest within 12 h to a few days after the initiation of mechanical ventilation. Various noninvasive and invasive methods have been developed to assess diaphragm function. The implementation of diaphragm-protective ventilation strategies is crucial for preventing diaphragm injuries. Furthermore, diaphragm neurostimulation emerges as a promising and novel treatment option. In this rapid review, our objective is to discuss the current understanding of ventilator-induced diaphragm dysfunction, diagnostic approaches, and updates on strategies for prevention and management.

Keywords: Diaphragm dysfunction; Liberation from mechanical ventilation; Mechanical ventilation.

Publication types

  • Review

MeSH terms

  • Diaphragm*
  • Humans
  • Lung
  • Respiration
  • Respiration, Artificial* / adverse effects
  • Ventilators, Mechanical