Chikungunya: a decade of burden in the Americas

William M de Souza; Guilherme S Ribeiro; Shirlene T S de Lima; Ronaldo de Jesus; Filipe R R Moreira; Charles Whittaker; Maria Anice M Sallum; Christine V F Carrington; Ester C Sabino; Uriel Kitron; Nuno R Faria; Scott C Weaver

doi:10.1016/j.lana.2023.100673

Chikungunya: a decade of burden in the Americas

Lancet Reg Health Am. 2024 Jan 8:30:100673. doi: 10.1016/j.lana.2023.100673. eCollection 2024 Feb.

Authors

William M de Souza^{1

2

3

4}, Guilherme S Ribeiro^{5

6}, Shirlene T S de Lima^{7

8}, Ronaldo de Jesus^{9

10}, Filipe R R Moreira¹¹, Charles Whittaker¹², Maria Anice M Sallum¹³, Christine V F Carrington¹⁴, Ester C Sabino^{15

16}, Uriel Kitron¹⁷, Nuno R Faria^{12

15

18}, Scott C Weaver^{2

3

4

19}

Affiliations

¹ Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky, College of Medicine, Lexington, KY, USA.
² Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.
³ World Reference Center for Emerging Viruses and Arboviruses, University of Texas Medical Branch, Galveston, TX, USA.
⁴ Global Virus Network, Baltimore, MD, USA.
⁵ Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Salvador, Bahia, Brazil.
⁶ Faculdade de Medicina da Bahia, Universidade Federal da Bahia, Salvador, Bahia, Brazil.
⁷ Laboratório Central de Saúde Pública do Ceará, Fortaleza, Ceará, Brazil.
⁸ Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, São Paulo, Brazil.
⁹ Coordenação Geral dos Laboratórios de Saúde Pública, Secretaria de Vigilância em Saúde, Ministério da Saúde, Brasília, Brazil.
¹⁰ Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
¹¹ Departamento de Genética, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
¹² MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, UK.
¹³ Departamento de Epidemiologia, Faculdade de Saúde Pública, Universidade de São Paulo, Brazil.
¹⁴ Department of Preclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Republic of Trinidad and Tobago.
¹⁵ Instituto de Medicina Tropical, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
¹⁶ Departamento de Moléstias Infecciosas e Parasitárias, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
¹⁷ Department of Environmental Sciences, Emory University, Atlanta, GA, USA.
¹⁸ Department of Biology, University of Oxford, Oxford, UK.
¹⁹ Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX, USA.

Abstract

In the Americas, one decade following its emergence in 2013, chikungunya virus (CHIKV) continues to spread and cause epidemics across the region. To date, 3.7 million suspected and laboratory-confirmed chikungunya cases have been reported in 50 countries or territories in the Americas. Here, we outline the current status and epidemiological aspects of chikungunya in the Americas and discuss prospects for future research and public health strategies to combat CHIKV in the region.

Keywords: Alphavirus; Americas; Arbovirus; Chikungunya virus; Mosquito-borne virus.

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Review

Abstract

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