Sporadic Polyps of the Colorectum

Ian Brown; Mark Bettington

doi:10.1016/j.gtc.2023.10.002

Sporadic Polyps of the Colorectum

Gastroenterol Clin North Am. 2024 Mar;53(1):155-177. doi: 10.1016/j.gtc.2023.10.002. Epub 2023 Dec 9.

Authors

Ian Brown¹, Mark Bettington²

Affiliations

¹ Envoi Pathology, Brisbane; Pathology Queensland, Royal Brisbane and Women's Hospital Cnr Herston and Bowen Bridge Roads, Herston Qld 4006, Australia; University of Queensland, St Lucia, Qld 4072, Australia. Electronic address: ianbrown@envoi.com.au.
² Envoi Pathology, Brisbane; University of Queensland, St Lucia, Qld 4072, Australia; Queensland Institute of Medical Research, 300 Herston Road, Herston QLD 4006, Australia.

PMID: 38280746
DOI: 10.1016/j.gtc.2023.10.002

Abstract

Colorectal polyps are common, and their diagnosis and classification represent a major component of gastrointestinal pathology practice. The majority of colorectal polyps represent precursors of either the chromosomal instability or serrated neoplasia pathways to colorectal carcinoma. Accurate reporting of these polyps has major implications for surveillance and thus for cancer prevention. In this review, we discuss the key histologic features of the major colorectal polyps with a particular emphasis on diagnostic pitfalls and areas of contention.

Keywords: Adenoma; Colorectal; Malignant polyp; Polyp; Serrated neoplasia.

Publication types

Review

MeSH terms

Adenoma* / diagnosis
Adenoma* / pathology
Colonic Polyps* / diagnosis
Colonic Polyps* / pathology
Colorectal Neoplasms* / diagnosis
Colorectal Neoplasms* / epidemiology
Colorectal Neoplasms* / genetics
Humans