Mechanisms of PAS Domain Signalling, from Sensing Varied Small Molecules and Peptides to Approved Pharmaceuticals and Use in Optogenetics

J Mol Biol. 2024 Feb 1;436(3):168457. doi: 10.1016/j.jmb.2024.168457. Epub 2024 Jan 24.

Authors

Sepideh Khorasanizadeh¹, Kevin H Gardner²

Affiliations

¹ University of Oxford, Oxford, UK. Electronic address: sepideh.khorasanizadeh@ndm.ox.ac.uk.
² CUNY Advanced Science Research Center, The City College of New York, USA. Electronic address: kgardner@gc.cuny.edu.

PMID: 38278435
DOI: 10.1016/j.jmb.2024.168457

No abstract available

Publication types

Editorial

MeSH terms

Animals
Aryl Hydrocarbon Receptor Nuclear Translocator* / chemistry
Basic Helix-Loop-Helix Transcription Factors* / chemistry
Humans
Optogenetics*
Peptides
Period Circadian Proteins* / chemistry
Pharmaceutical Preparations
Protein Domains
Signal Transduction*

Substances

Peptides
Pharmaceutical Preparations
Period Circadian Proteins
Aryl Hydrocarbon Receptor Nuclear Translocator
Basic Helix-Loop-Helix Transcription Factors