The application of nanotechnology in kidney transplantation

Nanomedicine (Lond). 2024 Feb;19(5):413-429. doi: 10.2217/nnm-2023-0286. Epub 2024 Jan 26.

Abstract

Kidney transplantation is a crucial treatment option for end-stage renal disease patients, but challenges related to graft function, rejection and immunosuppressant side effects persist. This review highlights the potential of nanotechnology in addressing these challenges. Nanotechnology offers innovative solutions to enhance organ preservation, evaluate graft function, mitigate ischemia-reperfusion injury and improve drug delivery for immunosuppressants. The integration of nanotechnology holds promise for improving outcomes in kidney transplantation.

Keywords: graft function evaluation; immunosuppressants; kidney transplantation; nanotechnology; organ preservation.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Kidney
  • Kidney Transplantation* / adverse effects
  • Organ Preservation
  • Reperfusion Injury* / drug therapy

Substances

  • Immunosuppressive Agents